Manufacturer: Gedeon Richter
Contents: Ethinylestradiol 0.03 mg, desogestrel 0.15 mg
Dosage: 1 tab daily for 21 days starting on the 1st day of the period followed by 7 tab-free days.
Contraindications: Known or suspected pregnancy, estrogen-dependent tumours, endometrial hyperplasia, undiagnosed vag bleeding. HTN, hyperlipoproteinaemia, diabetic angiopathy, cholelithiasis. Arterial thrombosis (eg MI, cerebrovascular events), venous thrombosis, venous thromboembolism, severe liver disease, cholestatic jaundice or hepatitis, Rotor syndrome, Dubin-Johnson syndrome, SLE. History during pregnancy of severe pruritus, herpes gestationis, jaundice.
Special Precautions: Cardiac insufficiency, renal impairment, HTN, epilepsy & migraine, DM, severe varicose veins, phlebitis, otosclerosis, sclerosis multiplex, chorea minor, latent tetany, benign uterine tumour, endometriosis or mastopathia, blood coagulation disorders.
Adverse Drug Reactions: Intermenstrual bleeding, changes in vag discharge, vag infections, aggravation of endometriosis. Breast tenderness, pain, enlargement, secretion. Nausea, vomiting, cholelithiasis, cholestatic jaundice, thrombosis, HTN, chloasma, erythema nodosum, rash, headache, migraine, mood changes, fluid retention, decreased glucose tolerance, changes in body wt.
Drug Interactions: Ampicillin, chloramphenicol, neomycin, penicillin-V, sulfonamides, tetracyclines, dihydroergotamine, tranquilizers, anticoagulants, coumarin or indandione derivatives, tricyclic antidepressants, maprotiline, oral antidiabetics, insulin, activated charcoal, laxatives, bromocriptine, hepatotoxic drugs.