DOSAGE FORM: Effervescent powder.
Paracetamol is the first choice for treatment of fever and pains. Paracetamol acts on heat-regulating centre of hypothalamus for hypothermia, increase in thermolysis due to vasodilation and peripheral hypervolemia leading to hypothermia in patients with fever, but rarely in the normal. Paracetamol is analgesic by elevation of pain suffered threshold.
At therapeutic dose, the analgesic and antipyretic action is equivalent to aspirin; however, paracetamol causes no adverse effects on cardiovascular and respiratory systems, no change in acid-base equilibrium, no irritation, scratch or gastrorrhagia, no action on glomeruli or bleeding time like aspirin or other salicylates. So, paracetamol is prior for analgesic and antipyretic action on children.
Hapacol Infants contains 80 mg of paracetamol that is suitable for infants under 3 years of age; it is prepared in effervescent powder, dissolved in water before use. The drug is quickly and mostly absorbed via digestive system.
For treatment of painful and/or febrile symptoms in cases of:
Hypersensitivity to paracetamol.
In some cases e.g. glucose-6-phosphate dehydrogenase (G6PD) deficiency; impaired hepatic function.
In cases of severe renal impairment.
Patients on low-sodium or sodium-free diets are warned that the drug contains 57.5 mg of ion sodium.
Concurrent use with anticoagulant (warfarin) may mildly enhance the effect of anticoagulant.
Allergic reactions have been rarely reported.
High doses and prolonged use of the drug may cause hepatic impairment (due to hepatolysis). Inform your physician about any adverse effects occur during the treatment.
DOSAGE & ADMINISTRATION
Dissolve the effervescent powder in some fresh water (sufficient for infants) until ending effervescence.
Orally taken every 6 hours, not more than 5 times daily.
Average usual dose: 10 - 15 mg / kg body-weight.
Total dose: maximally not more than 60mg / kg body-weight / 24 hours. Or the doses are as follows:
Infants 0 - 3 months of age: oral dose of ½ sachet.
Infants 4 - 11 months of age: oral dose of 1 sachet.
Infants 12 - 23 months of age: oral dose of 1½ sachets.
Infants 2 - 3 years of age: oral dose of 2 sachets.
Or as directed by the physician.
Notes: A long-term treatment should not be applied in infants if there is no physician's advice. Consult a physician if:
Read the directions carefully before use
Consult the physician for more information
24 months from the manufacturing date.
Store in cool, dry place; protected from light.