Hapacol 250mg
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Hapacol 250mg

  • Product Code:P00019
  • Availability:In Stock


  • Paracetamol...................... 250 mg
  • Excipients.q.s.................... 1 sachet
  • (Citric acid, mannitol, aspartame, sodium hydrocarbonate, PVP, ethanol 96%, refined sugar, sunset yellow, orange flavor).

DOSAGE FORMEffervescent powder.

Paracetamol is the first choice for treatment of fever and pains. Paracetamol acts o­n heat-regulating centre of hypothalamus for hypothermia, an increase in thermolysis due to vasodilation and peripheral hypervolemia leading to hypothermia in patients with fever, but rarely in the normal. Paracetamol is analgesic by the elevation of the pain threshold.
At therapeutic dose, the analgesic and antipyretic effect is equivalent to aspirin; however, paracetamol causes no adverse effects o­n cardiovascular and respiratory systems, no change of acid-base equilibrium, no irritation, scratch or gastrorrhagia, no action o­n glomeruli or bleeding time like aspirin or other salicylates. So, paracetamol is prior for analgesic, antipyretic actions o­n children.
Hapacol 250 containing 250 mg of paracetamol is prepared in the dosage form of effervescent powder, dissolved in water before use; therefore, it is suitable for analgesic - antipyretic actions o­n children. The drug is quickly and mostly absorbed by the digestive system.

For treatment of painful and/or febrile symptoms in cases of:

  • Cold, flu, headache, musculoskeletal pains, sprain, arthralgia,…
  • Upper respiratory tract infections: otalgia, sore throat, sinusitis caused by infections or weather,…
  • Postoperative tonsillectomy, tooth extraction, teething, toothache.


  • Hypersensitivity to paracetamol.
  • In some cases e.g. glucose-6-phosphate dehydrogenase (G6PD) deficiency; impaired hepatic function.
  • Patients with anemia or cardiopathy, pneumopathy, renopathy.

PRECAUTIONSPatients o­n low-sodium or sodium-free diets are warned that the drug contains 49.3 mg of ion sodium

Concurrent use with anticoagulant (warfarin) may mildly enhance the effect of anticoagulant. Drinking much alcohol or using alcohol for a long time may enhance a risk of hepatotoxicity by paracetamol. Concurrent administration of paracetamol and anticonvulsants (such as phenytoin, barbiturate, carbamazepine) and isoniazid may also increase hepatotoxicity by paracetamol.

Allergic reactions have been rarely reported. High doses and prolonged use of the drug may cause hepatic impairment (due to hepatolysis). Hypoleukemia, thrombocytopenia, anemia. Inform your physician about any adverse effects occur during the treatment.

Dissolve the effervescent powder in some fresh water (suitable for children) until ending effervescence.
Orally taken every 6 hours, not more than 5 times daily. The interval between oral doses should be at least 4 hours.
Average usual dose: 10 - 15 mg / kg body-weight.
Total doses: maximally not more than 60 mg / kg body-weight / 24 hours.
Or the doses are as follows:

  • Children 1 - 2 years of age: oral dose of ½ sachet.
  • Children 2 - 3 years of age: oral dose of ¾ sachet.
  • Children 4 - 6 years of age: oral dose of 1 sachet.
  • Children 7 - 9 years of age: oral dose of 1½ sachets.
  • Children 10 - 11 years of age: oral dose of 2 sachets.

Or as directed by the physician.

Notes: A long-term treatment should not be applied in children if there is no physician's advice, consult a physician if:

  • Any new symptoms occur.
  • High (39.50C) and prolonged (over 3 days) or recurrent fever.
  • Severe and prolonged pains (over 5 days).

Read the directions carefully before use.
Consult the physician for more information.

SHELF-LIFE24 months from the manufacturing date.
STORAGE CONDITIONSStore in cool, dry places; protected from light.

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